Coral Bilirubin Biochemistry Reagent (Medmeu)

Description

It Measures Serum Bilirubin.Coral Clinical Systems has answered these concerns of the busy laboratory professional by engineering the “Flexipour”reagent system which comprises of individual liquid stable components, which when mixed together in recommended ratios generate a dependable liquid stable working reagent. Depending on the usage, individual reagents may be poured at one go or flexibly in smaller volumes. Bilirubin is mainly formed from the heme portion of aged or damaged RBC’s. It then combines with albumin to form a complex which is not water soluble. This is referred to as indirect or unconjugated Bilirubin. In the liver this Bilirubin complex is combined with glucuronic acid into a water soluble conjugate. This is referred to as conjugated or direct Bilirubin. Elevated levels of bilirubin are found in liver diseases (Hepatitis, cirrhosis), excessive hemolysis / destruction of RBC (hemolytic jaundice) obstruction of the biliary tract (obstructive jaundice) and in drug induced reaction.sThe differentiation between the direct and indirect bilirubin is important in diagnosing the cause of hyperbilirubinemia. Bilirubin reacts with diazotised sulphanilic acid to form a coloured azobilirubin compound. The unconjugated bilirubin couples with the sulphanilic acid in the presence of a caffein-benzoate accelerator. The intensity of the colour formed is directly proportional to the amount of bilirubin present in the sample